Satellite meeting of World Parkinson’s Congress
8:00
9:00
Registration & Breakfast
Recent developments in GBA1 research and treatment
9:40 – 10:00
10:00 – 10:20
10:20 – 10:30
Overview of GBA1-targeting trials
Report on the ACTIVATE trial
Q&A
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11:00 – 11:20
11:20 – 11:40
11:40 – 12:00
12:00 – 12:20
12:20 – 12:30
Bidirectional regulation of GPNMB by β-glucocerebrosidase deficiency
The Cholinergic system in GBA1-PD
Targeting Lysosomal pH Restores Mitochondrial Quality Control in GBA1-Mutant Parkinson's Disease
Lysosomal glucocerebrosidase is needed for ciliary Hedgehog signaling
Q&A
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12:30
14:30
Lunch + Poster session
14:30 – 14:40
14:40 – 14:50
14:50 – 15:00
15:00 – 15:10
15:10 – 15:20
15:20 – 15:30
TBD
TBD
TBD
TBD
TBD
TBD
TBD
TBD
TBD
TBD
TBD
TBD
16:00 – 16:15
16:15 – 16:30
16:30 – 16:45
16:45 – 17:00
Update from company A
Update from company B
Update from company C
Q&A
Company A
Company B
Company C
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18:00
21:00
Cocktail Reception + meet the experts
8:00
9:00
Registration & Breakfast
9:10 – 9:40
9:40 – 10:00
10:00 – 10:10
Keynote presentation - Can gene editing become the future for GBA1-associated diseases?
Lipid nanoparticles for brain delivery
Q&A
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10:40 – 10:50
10:50 – 11:00
11:00 – 11:10
11:10 – 11:20
11:20 – 11:30
11:30 – 11:40
11:40 – 11:50
11:50 – 12:00
TBD
TBD
TBD
TBD
TBD
TBD
TBD
TBD
TBD
TBD
TBD
TBD
TBD
TBD
TBD
TBD
12:00
14:00
Lunch + Poster session
14:00 – 14:20
14:20 – 14:40
14:40 – 15:00
15:00 – 15:20
15:20 – 15:30
The global burden of GBA1-PD
GBA1 variant classification for clinical trials
Advances in biomarkers for GBA1 clinical research
Treatment of non-motor symptoms in GBA1-PD
Q&A
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16:00 – 16:20
16:20 – 16:40
16:40 – 17:00
Interplay between ATP13A2, glucocerebrosidase and BMP
Structural insights into the activation of TMEM175 by small molecule
Concluding remarks
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18:00
20:00
Event for people with PD – dinner + general public talk