Preliminary Conference Program

May 22-23, Phoenix, Arizona, US

3rd International GBA1 Meeting 2026

Satellite meeting of World Parkinson’s Congress

7:30

9:00

Registration & Breakfast

9:00

9:10

Topics

Welcome and opening remarks

Speaker

Ziv Gan-Or

9:10

9:40

Topics

Keynote presentation

Recent developments in GBA1 research and future perspectives

Speaker

Tony Futerman

9:40

10:30

9:40 – 10:00

10:00 – 10:20

10:20 – 10:30

Session

GBA1 therapeutics

Overview of GBA1-targeting trialsGBA1-targeting trials

Report on the ACTIVATE trial

Q&A

Speaker

Chair: TBD

Simon Stott

-

-

Details

30 mins

Coffee Break

11:00

12:30

11:00 – 11:20

11:20 – 11:40

11:40 – 12:00

12:00 – 12:20

12:20 – 12:30

Topics

Advances in GBA1 mechanisms

The cholinergic system in GBA1-PD

GBA1 and Lysosomal Oligogenic Risk for Parkinson’s Disease

Targeting Lysosomal pH Restores Mitochondrial Quality Control in GBA1-Mutant Parkinson’s Disease

Lysosomal glucocerebrosidase is needed for ciliary Hedgehog signaling

Q&A

Speaker

Chair: Jia Nee Foo

Teus van Laar

Joshua Shulman

Preethi Sheshadri

Suzanne Pfeffer

Details

12:30

12:40

Lunch + Poster session

14:30

15:30

14:30 – 14:40

14:40 – 14:50

14:50 – 15:00

15:00 – 15:10

15:10 – 15:20

15:20 – 15:30

Topics

Data Blitz 1 (selected from abstracts)

TBD

TBD

TBD

TBD

TBD

TBD

Speaker

Chair: TBD

TBD

TBD

TBD

TBD

TBD

TBD

Details

30 mins

Coffee Break

16:00

17:00

16:00 – 16:15

16:15 – 16:30

16:30 – 16:45

16:45 – 17:00

Topics

In the pipeline: updates from pharma on ongoing preclinical studies and clinical trials

Update from company A

Update from company B

Update from company C

Q&A

Speaker

Chair: Ziv Gan-Or

Company A

Company B

Company C

-

Details

18:00

21:00

Cocktail Reception + meet the experts

08:00

09:00

Registration & Breakfast

09:00

09:10

Topics

Announcement of trainee awards for best poster /oral presentation

Speaker

Ziv Gan-Or

09:10

10:10

9:10 – 9:40

9:40 – 10:00

10:00 – 10:10

Session

Novel therapeutic approaches for GBA1-associated diseases

Keynote presentation – Base editing for GD and GBA1-associated PD: lessons from Tay Sachs

GBA1 in neurons vs astrocytes

Q&A

Speaker

Chair: Shalini Padmanabhan

Richard Proia

Marie Davis

Details

30 mins

Coffee Break

10:40

12:00

10:40 – 10:50

10:50 – 11:00

11:00 – 11:10

11:10 – 11:20

11:20 – 11:30

11:30 – 11:40

11:40 – 11:50

11:50 – 12:00

Topics

Data Blitz 2

TBD

TBD

TBD

TBD

TBD

TBD

TBD

TBD

Speaker

Chair: Joe Mazzuli

TBD

TBD

TBD

TBD

TBD

TBD

TBD

TBD

Details

12:00

14:00

Lunch + Poster session

14:00

15:30

14:00 – 14:20

14:20 – 14:40

14:40 – 15:00

15:00 – 15:20

15:20 – 15:30

Topics

Clinical considerations in GBA1-PD

The global burden of GBA1-PD

Treatment of non-motor symptoms in GBA1-PD

Biomarkers for GBA1-PD

Challenges in genetic counseling for GBA1 in PD

Q&A

Speaker

Chair: TBD

Ziv Gan-Or

Avner Thaler

TBD

Valentina Caceres

-

Details

30 mins

Coffee Break

16:00

17:00

16:00 – 16:20

16:20 – 16:40

16:40 – 16:50

16:50 – 17:00

Topics

GBA1 modifiers

Bidirectional regulation of GPNMB by β- glucocerebrosidase deficiency

CRISPR screening for modifiers of GCase activity

Q&A

Concluding remarks

Speaker

Chair: TBD

Yu Chen

Melissa Roberts

-

Ziv Gan-Or

Details

18:00

20:00

Event for people with PD – dinner + general public talk